What symptoms can be a manifestation of an incipient or ongoing infection:

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1) Fever is the most common symptom of an infectious disease. It can be a high temperature for several days without characteristic symptoms of acute respiratory infections, or, conversely, a low (subfebrile) temperature for a long time (2 weeks or more) without a specific reason. 2) Discoloration of the skin and sclera of the eyes (jaundice), discoloration of urine and stools. 3) The appearance of a rash of any nature, especially against the background of a rise in temperature. 4) Allergic manifestations are long-term and without much success after treatment with an allergist. 5) Stool disorders of a different nature (from frequent for a short period of time to semi-liquid for 2 or more weeks). 6) Nonspecific symptoms: weakness, fatigue, headaches, muscle weakness and others. 7) Any symptoms after a characteristic epidemiological history (contact with a sick person, bites of insects, rodents, contact with sick cattle, other animals and birds, leaving the country with a visit to any countries with a subtropical and tropical climate).

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These symptoms should prompt you to see your doctor immediately. The earliest method of primary diagnosis of an infectious disease is a doctor's consultation-infectionist (in the absence of one, a therapist). The volume of diagnostic studies ("analyzes") depends on the correctness of the preliminary diagnosis. To examine a patient for the presence of an infectious disease, two large groups of specific methods are used:

1) Direct diagnostic methods (microbiological methods, PCR diagnostics, ELISA method with the determination of pathogen antigens). 2) Indirect methods (serological reactions for the detection of antibodies - ELISA, RA, RNGA, RPGA, RTGA, RN and others).

Direct diagnostic methods are aimed at identifying pathogens and their antigens. Microbiological studies are carried out with suspicion of bacterial and viral infections by sowing material from the patient on special nutrient media and a kind of growing colonies of pathogens in certain comfortable conditions for them. The advantage of such methods in identifying the pathogen itself, however, a number of studies are carried out for a long time - up to 10 days.

In this regard, PCR diagnostics came to the rescue - the determination of the antigens of pathogens (DNA, RNA). The advantage of PCR diagnostics is the high specificity of the method with the determination of even one nucleic acid molecule (DNA, RNA) in living or dead material.

Parasitological studies of materials for the detection of protozoan and helminth eggs are also direct methods. The material for research with direct methods is almost any biological material: blood, mucus of the nose and throat, urine, bile, cerebrospinal fluid, biopsies of tissues and organs.

The result of indirect diagnostic methods is the detection in the blood of specific antibodies to any disease - these are immunoglobulins, which are formed in response to infectious agents entering the human body. This is a method of indirect detection of the causative agent of the disease by the formed antibodies, and it is possible to assume both an acute infection and an exacerbation of a chronic disease. Canadian Pharmacies Online can be qualitative or quantitative, expressed in antibody titers.

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IgG can circulate for life, forming immunity to a specific infection. The concentration of antibodies in blood serum depends on a number of factors: the time from the moment of infection, the antigenic properties of the causative agent of the disease, the state of the immune system of the person himself at the time of infection. The material for indirect methods is mainly the patient's blood serum taken on an empty stomach.